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Phospholipid prodrug conjugates of insoluble chemotherapeutic agents for ultrasound targeted drug delivery

The hydrophobicity and high potency of many therapeutic agents makes them difficult to use effectively in clinical practice. This work focuses on conjugating phospholipid tails (2T) onto podophyllotoxin (P) and its analogue (N) using a linker and characterizing the effects of their incorporation int...

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Detalhes bibliográficos
Publicado no:Nanotheranostics
Main Authors: Márquez, Mendi G., Dotson, Rachel, Pias, Sally, Frolova, Liliya V., Tartis, Michaelann S.
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940203/
https://ncbi.nlm.nih.gov/pubmed/31911893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ntno.37738
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