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The C-Terminal Heme Regulatory Motifs of Heme Oxygenase-2 Are Redox-Regulated Heme Binding Sites

[Image: see text] Heme oxygenase-2 (HO2), an enzyme that catalyzes the conversion of heme to biliverdin, contains three heme regulatory motifs (HRMs) centered at Cys127, Cys265, and Cys282. Previous studies using the soluble form of human HO2 spanning residues 1–288 (HO2(sol)) have shown that a disu...

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Détails bibliographiques
Publié dans:Biochemistry
Auteurs principaux: Fleischhacker, Angela S., Sharma, Ajay, Choi, Michelle, Spencer, Andrea M., Bagai, Ireena, Hoffman, Brian M., Ragsdale, Stephen W.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4478078/
https://ncbi.nlm.nih.gov/pubmed/25853617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00266
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