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Mesenchymal stromal cells of osteosarcoma patients do not show evidence of neoplastic changes during long-term culture

BACKGROUND: In vitro expanded mesenchymal stromal cells (MSCs) are increasingly used as experimental cellular therapy. However, there have been concerns regarding the safety of their use, particularly with regard to possible oncogenic transformation. MSCs are the hypothesized precursor cells of high...

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Bibliografische gegevens
Gepubliceerd in:Clin Sarcoma Res
Hoofdauteurs: Buddingh, Emilie P, Ruslan, S Eriaty N, Reijnders, Christianne M A, Szuhai, Karoly, Kuijjer, Marieke L, Roelofs, Helene, Hogendoorn, Pancras C W, Maarten Egeler, R, Cleton-Jansen, Anne-Marie, Lankester, Arjan C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477606/
https://ncbi.nlm.nih.gov/pubmed/26106474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13569-015-0031-1
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