Mesenchymal stromal cells of osteosarcoma patients do not show evidence of neoplastic changes during long-term culture

BACKGROUND: In vitro expanded mesenchymal stromal cells (MSCs) are increasingly used as experimental cellular therapy. However, there have been concerns regarding the safety of their use, particularly with regard to possible oncogenic transformation. MSCs are the hypothesized precursor cells of high...

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Detalhes bibliográficos
Publicado no:Clin Sarcoma Res
Main Authors: Buddingh, Emilie P, Ruslan, S Eriaty N, Reijnders, Christianne M A, Szuhai, Karoly, Kuijjer, Marieke L, Roelofs, Helene, Hogendoorn, Pancras C W, Maarten Egeler, R, Cleton-Jansen, Anne-Marie, Lankester, Arjan C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477606/
https://ncbi.nlm.nih.gov/pubmed/26106474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13569-015-0031-1
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