Chemotherapy-resistant osteosarcoma is highly susceptible to IL-15-activated allogeneic and autologous NK cells

High-grade osteosarcoma occurs predominantly in adolescents and young adults and has an overall survival rate of about 60%, despite chemotherapy and surgery. Therefore, novel treatment modalities are needed to prevent or treat recurrent disease. Natural killer (NK) cells are lymphocytes with cytotox...

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Bibliographic Details
Main Authors: Buddingh, Emilie P., Schilham, Marco W., Ruslan, S. Eriaty N., Berghuis, Dagmar, Szuhai, Karoly, Suurmond, Jolien, Taminiau, Antonie H. M., Gelderblom, Hans, Egeler, R. Maarten, Serra, Massimo, Hogendoorn, Pancras C. W., Lankester, Arjan C.
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2011
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061210/
https://ncbi.nlm.nih.gov/pubmed/21240486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-010-0965-3
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