Chemotherapy-resistant osteosarcoma is highly susceptible to IL-15-activated allogeneic and autologous NK cells

High-grade osteosarcoma occurs predominantly in adolescents and young adults and has an overall survival rate of about 60%, despite chemotherapy and surgery. Therefore, novel treatment modalities are needed to prevent or treat recurrent disease. Natural killer (NK) cells are lymphocytes with cytotox...

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Bibliographische Detailangaben
Hauptverfasser: Buddingh, Emilie P., Schilham, Marco W., Ruslan, S. Eriaty N., Berghuis, Dagmar, Szuhai, Karoly, Suurmond, Jolien, Taminiau, Antonie H. M., Gelderblom, Hans, Egeler, R. Maarten, Serra, Massimo, Hogendoorn, Pancras C. W., Lankester, Arjan C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer-Verlag 2011
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061210/
https://ncbi.nlm.nih.gov/pubmed/21240486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-010-0965-3
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