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An integrated approach to reveal miRNAs’ impacts on the functional consequence of copy number alterations in cancer
Copy number alteration (CNA) is known to induce gene expression changes mainly through dosage effect, and therefore affect the initiation and progression of tumor. However, tumor samples exhibit heterogeneity in gene dosage sensitivity due to the complicated mechanisms of transcriptional regulation....
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4477324/ https://ncbi.nlm.nih.gov/pubmed/26099552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11567 |
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