An integrated approach to reveal miRNAs’ impacts on the functional consequence of copy number alterations in cancer

Copy number alteration (CNA) is known to induce gene expression changes mainly through dosage effect, and therefore affect the initiation and progression of tumor. However, tumor samples exhibit heterogeneity in gene dosage sensitivity due to the complicated mechanisms of transcriptional regulation....

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Li, Kening, Liu, Yongjing, Zhou, Yuanshuai, Zhang, Rui, Zhao, Ning, Yan, Zichuang, Zhang, Qiang, Zhang, Shujuan, Qiu, Fujun, Xu, Yan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477324/
https://ncbi.nlm.nih.gov/pubmed/26099552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11567
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