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Insights on the functional interactions between miRNAs and copy number variations in the aging brain

MicroRNAs (miRNAs) are regulatory genetic elements that coordinate the expression of thousands of genes and play important roles in brain aging and neurodegeneration. DNA polymorphisms affecting miRNA biogenesis, dosage, and gene targeting may represent potentially functional variants. The consequen...

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Autors principals: Persengiev, Stephan, Kondova, Ivanela, Bontrop, Ronald
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3788589/
https://ncbi.nlm.nih.gov/pubmed/24106459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2013.00032
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