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PAX3 and ETS1 synergistically activate MET expression in melanoma cells
Melanoma is a highly aggressive disease that is difficult to treat due to rapid tumor growth, apoptotic resistance, and high metastatic potential. The MET tyrosine kinase receptor promotes many of these cellular processes, and while MET is often overexpressed in melanoma, the mechanism driving this...
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| Veröffentlicht in: | Oncogene |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4476961/ https://ncbi.nlm.nih.gov/pubmed/25531327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.420 |
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