PAX3 and ETS1 synergistically activate MET expression in melanoma cells

Melanoma is a highly aggressive disease that is difficult to treat due to rapid tumor growth, apoptotic resistance, and high metastatic potential. The MET tyrosine kinase receptor promotes many of these cellular processes, and while MET is often overexpressed in melanoma, the mechanism driving this...

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Udgivet i:Oncogene
Main Authors: Kubic, Jennifer D., Little, Elizabeth C., Lui, Jason W., Iizuka, Takumi, Lang, Deborah
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476961/
https://ncbi.nlm.nih.gov/pubmed/25531327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.420
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