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PAX3 and ETS1 synergistically activate MET expression in melanoma cells

Melanoma is a highly aggressive disease that is difficult to treat due to rapid tumor growth, apoptotic resistance, and high metastatic potential. The MET tyrosine kinase receptor promotes many of these cellular processes, and while MET is often overexpressed in melanoma, the mechanism driving this...

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Détails bibliographiques
Publié dans:Oncogene
Auteurs principaux: Kubic, Jennifer D., Little, Elizabeth C., Lui, Jason W., Iizuka, Takumi, Lang, Deborah
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476961/
https://ncbi.nlm.nih.gov/pubmed/25531327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.420
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