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PAX3 and ETS1 synergistically activate MET expression in melanoma cells

Melanoma is a highly aggressive disease that is difficult to treat due to rapid tumor growth, apoptotic resistance, and high metastatic potential. The MET tyrosine kinase receptor promotes many of these cellular processes, and while MET is often overexpressed in melanoma, the mechanism driving this...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Kubic, Jennifer D., Little, Elizabeth C., Lui, Jason W., Iizuka, Takumi, Lang, Deborah
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476961/
https://ncbi.nlm.nih.gov/pubmed/25531327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.420
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