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PAX3 and FOXD3 Promote CXCR4 Expression in Melanoma

Metastatic melanoma is an aggressive and deadly disease. The chemokine receptor CXCR4 is active in melanoma metastasis, although the mechanism for the promotion and maintenance of CXCR4 expression in these cells is mostly unknown. Here, we find melanoma cells express two CXCR4 isoforms, the common v...

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Vydáno v:J Biol Chem
Hlavní autoři: Kubic, Jennifer D., Lui, Jason W., Little, Elizabeth C., Ludvik, Anton E., Konda, Sasank, Salgia, Ravi, Aplin, Andrew E., Lang, Deborah
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571945/
https://ncbi.nlm.nih.gov/pubmed/26205821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.670976
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