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Novel therapeutic approaches for hepatitis B virus covalently closed circular DNA

Hepatitis B virus (HBV) infection is a major global health problem. Although current therapies, such as the use of nucleos(t)ide analogs, inhibit HBV replication efficiently, they do not eliminate covalently closed circular DNA (cccDNA), which persists in hepatocyte nuclei. As HBV cccDNA is a viral...

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Bibliografiske detaljer
Udgivet i:World J Gastroenterol
Main Authors: Ohno, Motoko, Otsuka, Motoyuki, Kishikawa, Takahiro, Yoshikawa, Takeshi, Takata, Akemi, Koike, Kazuhiko
Format: Artigo
Sprog:Inglês
Udgivet: Baishideng Publishing Group Inc 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476870/
https://ncbi.nlm.nih.gov/pubmed/26109795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v21.i23.7084
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