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Novel therapeutic approaches for hepatitis B virus covalently closed circular DNA

Hepatitis B virus (HBV) infection is a major global health problem. Although current therapies, such as the use of nucleos(t)ide analogs, inhibit HBV replication efficiently, they do not eliminate covalently closed circular DNA (cccDNA), which persists in hepatocyte nuclei. As HBV cccDNA is a viral...

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Bibliografski detalji
Izdano u:World J Gastroenterol
Glavni autori: Ohno, Motoko, Otsuka, Motoyuki, Kishikawa, Takahiro, Yoshikawa, Takeshi, Takata, Akemi, Koike, Kazuhiko
Format: Artigo
Jezik:Inglês
Izdano: Baishideng Publishing Group Inc 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476870/
https://ncbi.nlm.nih.gov/pubmed/26109795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v21.i23.7084
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