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Novel therapeutic approaches for hepatitis B virus covalently closed circular DNA
Hepatitis B virus (HBV) infection is a major global health problem. Although current therapies, such as the use of nucleos(t)ide analogs, inhibit HBV replication efficiently, they do not eliminate covalently closed circular DNA (cccDNA), which persists in hepatocyte nuclei. As HBV cccDNA is a viral...
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| 發表在: | World J Gastroenterol |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Baishideng Publishing Group Inc
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4476870/ https://ncbi.nlm.nih.gov/pubmed/26109795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v21.i23.7084 |
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