Host Subtraction, Filtering and Assembly Validations for Novel Viral Discovery Using Next Generation Sequencing Data

The use of next generation sequencing (NGS) to identify novel viral sequences from eukaryotic tissue samples is challenging. Issues can include the low proportion and copy number of viral reads and the high number of contigs (post-assembly), making subsequent viral analysis difficult. Comparison of...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Daly, Gordon M., Leggett, Richard M., Rowe, William, Stubbs, Samuel, Wilkinson, Maxim, Ramirez-Gonzalez, Ricardo H., Caccamo, Mario, Bernal, William, Heeney, Jonathan L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476701/
https://ncbi.nlm.nih.gov/pubmed/26098299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129059
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