Host Subtraction, Filtering and Assembly Validations for Novel Viral Discovery Using Next Generation Sequencing Data

The use of next generation sequencing (NGS) to identify novel viral sequences from eukaryotic tissue samples is challenging. Issues can include the low proportion and copy number of viral reads and the high number of contigs (post-assembly), making subsequent viral analysis difficult. Comparison of...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Daly, Gordon M., Leggett, Richard M., Rowe, William, Stubbs, Samuel, Wilkinson, Maxim, Ramirez-Gonzalez, Ricardo H., Caccamo, Mario, Bernal, William, Heeney, Jonathan L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476701/
https://ncbi.nlm.nih.gov/pubmed/26098299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129059
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