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Antiproliferative effects of mitochondria-targeted cationic antioxidants and analogs: Role of mitochondrial bioenergetics and energy-sensing mechanism

One of the proposed mechanisms for tumor proliferation involves redox signaling mediated by reactive oxygen species such as superoxide and hydrogen peroxide generated at moderate levels. Thus, the antiproliferative and anti-tumor effects of certain antioxidants were attributed to their ability to mi...

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Foilsithe in:Cancer Lett
Main Authors: Cheng, Gang, Zielonka, Jacek, McAllister, Donna, Hardy, Micael, Ouari, Olivier, Joseph, Joy, Dwinell, Michael B., Kalyanaraman, Balaraman
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476640/
https://ncbi.nlm.nih.gov/pubmed/26004344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.05.016
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