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Prion protein functions as a ferrireductase partner for ZIP14 and DMT1

Excess circulating iron is stored in the liver, and requires reduction of non-Tf-bound-iron (NTBI) and transferrin (Tf)-iron at the plasma membrane and endosomes respectively by ferrireductase (FR) proteins for transport across biological membranes through divalent metal transporters. Here, we repor...

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Publicat a:Free Radic Biol Med
Autors principals: Tripathi, Ajai K., Haldar, Swati, Qian, Juan, Beserra, Amber, Suda, Srinivas, Singh, Ajay, Hopfer, Ulrich, Chen, Shu G., Garrick, Michael D., Turner, Jerrold R., Knutson, Mitchell D., Singh, Neena
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476631/
https://ncbi.nlm.nih.gov/pubmed/25862412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.03.037
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