A Sex-Specific MicroRNA-96/5-Hydroxytryptamine 1B Axis Influences Development of Pulmonary Hypertension

Rationale: Females are predisposed to pulmonary arterial hypertension (PAH); evidence suggests that serotonin, mutations in the bone morphogenetic protein receptor (BMPR) II gene, and estrogens influence development of PAH. The 5-hydroxytryptamine 1B receptor (5-HT(1B)R) mediates human pulmonary art...

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Publicat a:Am J Respir Crit Care Med
Autors principals: Wallace, Emma, Morrell, Nicholas W., Yang, Xudong D., Long, Lu, Stevens, Hannah, Nilsen, Margaret, Loughlin, Lynn, Mair, Kirsty M., Baker, Andrew H., MacLean, Margaret R.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476563/
https://ncbi.nlm.nih.gov/pubmed/25871906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201412-2148OC
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