Mechanism-Based Classification of PAH Mixtures to Predict Carcinogenic Potential

We have previously shown that relative potency factors and DNA adduct measurements are inadequate for predicting carcinogenicity of certain polycyclic aromatic hydrocarbons (PAHs) and PAH mixtures, particularly those that function through alternate pathways or exhibit greater promotional activity co...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Tilton, Susan C., Siddens, Lisbeth K., Krueger, Sharon K., Larkin, Andrew J., Löhr, Christiane V., Williams, David E., Baird, William M., Waters, Katrina M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Polyaromatic Hydrocarbons and Carcinogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476464/
https://ncbi.nlm.nih.gov/pubmed/25908611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv080
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