Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs

Polycyclic aromatic hydrocarbons (PAHs) are priority environmental contaminants that exhibit mutagenic, carcinogenic, proinflammatory, and teratogenic properties. Oxygen-substituted PAHs (OPAHs) are formed during combustion processes and via phototoxidation and biological degradation of parent (unsu...

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Pubblicato in:Toxicol Sci
Autori principali: Goodale, B. C., La Du, J., Tilton, S. C., Sullivan, C. M., Bisson, W. H., Waters, K. M., Tanguay, R. L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
Soggetti:
Polyaromatic Hydrocarbons and the Aryl Hydrocarbon Receptor
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612346/
https://ncbi.nlm.nih.gov/pubmed/26141390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv139
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