Application of a Fuzzy Neural Network Model in Predicting Polycyclic Aromatic Hydrocarbon- Mediated Perturbations of the Cyp1b1 Transcriptional Regulatory Network in Mouse Skin

Polycyclic aromatic hydrocarbons (PAHs) are present in the environment as complex mixtures with components that have diverse carcinogenic potencies and mostly unknown interactive effects. Non-additive PAH interactions have been observed in regulation of cytochrome P450 (CYP) gene expression in the C...

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Main Authors: Larkin, Andrew, Siddens, Lisbeth K., Krueger, Sharon K., Tilton, Susan C., Waters, Katrina M., Williams, David E., Baird, William M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626406/
https://ncbi.nlm.nih.gov/pubmed/23274566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2012.12.011
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