NOS-2 Inhibition in Phosgene-Induced Acute Lung Injury

Phosgene exposure via an industrial or warfare release produces severe acute lung injury (ALI) with high mortality, characterized by massive pulmonary edema, disruption of epithelial tight junctions, surfactant dysfunction, and oxidative stress. There are no targeted treatments for phosgene-induced...

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Vydáno v:Toxicol Sci
Hlavní autoři: Filipczak, Piotr T., Senft, Albert P., Seagrave, JeanClare, Weber, Waylon, Kuehl, Philip J., Fredenburgh, Laura E., McDonald, Jacob D., Baron, Rebecca M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
Attenuation of Phosgene-Induced Pulmonary Damage
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476462/
https://ncbi.nlm.nih.gov/pubmed/25870319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv072
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