NOS-2 Inhibition in Phosgene-Induced Acute Lung Injury

Phosgene exposure via an industrial or warfare release produces severe acute lung injury (ALI) with high mortality, characterized by massive pulmonary edema, disruption of epithelial tight junctions, surfactant dysfunction, and oxidative stress. There are no targeted treatments for phosgene-induced...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Filipczak, Piotr T., Senft, Albert P., Seagrave, JeanClare, Weber, Waylon, Kuehl, Philip J., Fredenburgh, Laura E., McDonald, Jacob D., Baron, Rebecca M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Attenuation of Phosgene-Induced Pulmonary Damage
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476462/
https://ncbi.nlm.nih.gov/pubmed/25870319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv072
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