An N-terminal formyl methionine on COX 1 is required for the assembly of cytochrome c oxidase

Protein synthesis in mitochondria is initiated by formylmethionyl-tRNA(Met) (fMet-tRNA(Met)), which requires the activity of the enzyme MTFMT to formylate the methionyl group. We investigated the molecular consequences of mutations in MTFMT in patients with Leigh syndrome or cardiomyopathy. All pati...

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Bibliografiset tiedot
Julkaisussa:Hum Mol Genet
Päätekijät: Hinttala, Reetta, Sasarman, Florin, Nishimura, Tamiko, Antonicka, Hana, Brunel-Guitton, Catherine, Schwartzentruber, Jeremy, Fahiminiya, Somayyeh, Majewski, Jacek, Faubert, Denis, Ostergaard, Elsebet, Smeitink, Jan A., Shoubridge, Eric A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2015
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476453/
https://ncbi.nlm.nih.gov/pubmed/25911677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv149
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