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Genetic drift of human coronavirus OC43 spike gene during adaptive evolution

Coronaviruses (CoVs) continuously threaten human health. However, to date, the evolutionary mechanisms that govern CoV strain persistence in human populations have not been fully understood. In this study, we characterized the evolution of the major antigen-spike (S) gene in the most prevalent human...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Ren, Lili, Zhang, Yue, Li, Jianguo, Xiao, Yan, Zhang, Jing, Wang, Ying, Chen, Lan, Paranhos-Baccalà, Gláucia, Wang, Jianwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476415/
https://ncbi.nlm.nih.gov/pubmed/26099036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11451
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