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Genetic drift of human coronavirus OC43 spike gene during adaptive evolution

Coronaviruses (CoVs) continuously threaten human health. However, to date, the evolutionary mechanisms that govern CoV strain persistence in human populations have not been fully understood. In this study, we characterized the evolution of the major antigen-spike (S) gene in the most prevalent human...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Ren, Lili, Zhang, Yue, Li, Jianguo, Xiao, Yan, Zhang, Jing, Wang, Ying, Chen, Lan, Paranhos-Baccalà, Gláucia, Wang, Jianwei
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476415/
https://ncbi.nlm.nih.gov/pubmed/26099036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11451
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