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Genetic drift of human coronavirus OC43 spike gene during adaptive evolution

Coronaviruses (CoVs) continuously threaten human health. However, to date, the evolutionary mechanisms that govern CoV strain persistence in human populations have not been fully understood. In this study, we characterized the evolution of the major antigen-spike (S) gene in the most prevalent human...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ren, Lili, Zhang, Yue, Li, Jianguo, Xiao, Yan, Zhang, Jing, Wang, Ying, Chen, Lan, Paranhos-Baccalà, Gláucia, Wang, Jianwei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476415/
https://ncbi.nlm.nih.gov/pubmed/26099036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11451
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