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Evidence for adaptive evolution in the receptor-binding domain of seasonal coronaviruses OC43 and 229e

Seasonal coronaviruses (OC43, 229E, NL63, and HKU1) are endemic to the human population, regularly infecting and reinfecting humans while typically causing asymptomatic to mild respiratory infections. It is not known to what extent reinfection by these viruses is due to waning immune memory or antig...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Kistler, Kathryn E, Bedford, Trevor
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7861616/
https://ncbi.nlm.nih.gov/pubmed/33463525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64509
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