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Pregnane X receptor knockout mice display osteopenia with reduced bone formation and enhanced bone resorption

The steroid and xenobiotic receptor (SXR) and its murine ortholog pregnane X receptor (PXR) are nuclear receptors that are expressed mainly in the liver and intestine where they function as xenobiotic sensors. In addition to its role as a xenobiotic sensor, previous studies in our laboratories and e...

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Podrobná bibliografie
Vydáno v:J Endocrinol
Hlavní autoři: Azuma, Kotaro, Casey, Stephanie C, Ito, Masako, Urano, Tomohiko, Horie, Kuniko, Ouchi, Yasuyoshi, Kirchner, Séverine, Blumberg, Bruce, Inoue, Satoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476281/
https://ncbi.nlm.nih.gov/pubmed/20876238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-10-0208
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