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Pregnane X Receptor Knockout Mice Display Aging-Dependent Wearing of Articular Cartilage

Steroid and xenobiotic receptor (SXR) and its murine ortholog, pregnane X receptor (PXR), are nuclear receptors that are expressed at high levels in the liver and the intestine where they function as xenobiotic sensors that induce expression of genes involved in detoxification and drug excretion. Re...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Azuma, Kotaro, Casey, Stephanie C., Urano, Tomohiko, Horie-Inoue, Kuniko, Ouchi, Yasuyoshi, Blumberg, Bruce, Inoue, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352085/
https://ncbi.nlm.nih.gov/pubmed/25749104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119177
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