Focusing and sustaining the antitumor CTL effector killer response by agonist anti-CD137 mAb

Cancer immunotherapy is undergoing significant progress due to recent clinical successes by refined adoptive T-cell transfer and immunostimulatory monoclonal Ab (mAbs). B16F10-derived OVA-expressing mouse melanomas resist curative immunotherapy with either adoptive transfer of activated anti-OVA OT1...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Weigelin, Bettina, Bolaños, Elixabet, Teijeira, Alvaro, Martinez-Forero, Ivan, Labiano, Sara, Azpilikueta, Arantza, Morales-Kastresana, Aizea, Quetglas, José I., Wagena, Esther, Sánchez-Paulete, Alfonso Rodríguez, Chen, Lieping, Friedl, Peter, Melero, Ignacio
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475992/
https://ncbi.nlm.nih.gov/pubmed/26034288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1506357112
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