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Cutting Edge: Caspase-11 limits the response of CD8(+) T cells to low abundance and low affinity antigens
Inflammatory caspases, including caspase-11, are upregulated in CD8(+) T cells after antigen-specific activation, but little is known about their function in T cells. We report that caspase-11-deficient (Casp11(−/−)) T cells proliferated more readily in response to low affinity and low abundance lig...
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| Publié dans: | J Immunol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4475665/ https://ncbi.nlm.nih.gov/pubmed/25980012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500812 |
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