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Cutting Edge: Caspase-11 limits the response of CD8(+) T cells to low abundance and low affinity antigens

Inflammatory caspases, including caspase-11, are upregulated in CD8(+) T cells after antigen-specific activation, but little is known about their function in T cells. We report that caspase-11-deficient (Casp11(−/−)) T cells proliferated more readily in response to low affinity and low abundance lig...

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Bibliografiska uppgifter
I publikationen:J Immunol
Huvudupphovsmän: Bergsbaken, Tessa, Bevan, Michael J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475665/
https://ncbi.nlm.nih.gov/pubmed/25980012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500812
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