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Short loop length and high thermal stability determine genomic instability induced by G-quadruplex-forming minisatellites

G-quadruplexes (G4) are polymorphic four-stranded structures formed by certain G-rich nucleic acids, with various biological roles. However, structural features dictating their formation and/or functionin vivo are unknown. InS. cerevisiae, the pathological persistency of G4 within the CEB1 minisatel...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Piazza, Aurèle, Adrian, Michael, Samazan, Frédéric, Heddi, Brahim, Hamon, Florian, Serero, Alexandre, Lopes, Judith, Teulade-Fichou, Marie-Paule, Phan, Anh Tuân, Nicolas, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475404/
https://ncbi.nlm.nih.gov/pubmed/25956747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490702
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