Genetic instability triggered by G-quadruplex interacting Phen-DC compounds in Saccharomyces cerevisiae

G-quadruplexes are nucleic acid secondary structures for which many biological roles have been proposed but whose existence in vivo has remained elusive. To assess their formation, highly specific G-quadruplex ligands are needed. Here, we tested Phen-DC(3) and Phen-DC(6), two recently released ligan...

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Библиографические подробности
Главные авторы: Piazza, Aurèle, Boulé, Jean-Baptiste, Lopes, Judith, Mingo, Katie, Largy, Eric, Teulade-Fichou, Marie-Paule, Nicolas, Alain
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2010
Предметы:
Genome Integrity, Repair and Replication
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910037/
https://ncbi.nlm.nih.gov/pubmed/20223771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq136
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