Smg6/Est1 licenses embryonic stem cell differentiation via nonsense-mediated mRNA decay

Nonsense-mediated mRNA decay (NMD) is a post-transcriptional mechanism that targets aberrant transcripts and regulates the cellular RNA reservoir. Genetic modulation in vertebrates suggests that NMD is critical for cellular and tissue homeostasis, although the underlying mechanism remains elusive. H...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Li, Tangliang, Shi, Yue, Wang, Pei, Guachalla, Luis Miguel, Sun, Baofa, Joerss, Tjard, Chen, Yu-Sheng, Groth, Marco, Krueger, Anja, Platzer, Matthias, Yang, Yun-Gui, Rudolph, Karl Lenhard, Wang, Zhao-Qi
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475398/
https://ncbi.nlm.nih.gov/pubmed/25770585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489947
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