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Smg6/Est1 licenses embryonic stem cell differentiation via nonsense-mediated mRNA decay

Nonsense-mediated mRNA decay (NMD) is a post-transcriptional mechanism that targets aberrant transcripts and regulates the cellular RNA reservoir. Genetic modulation in vertebrates suggests that NMD is critical for cellular and tissue homeostasis, although the underlying mechanism remains elusive. H...

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Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Li, Tangliang, Shi, Yue, Wang, Pei, Guachalla, Luis Miguel, Sun, Baofa, Joerss, Tjard, Chen, Yu-Sheng, Groth, Marco, Krueger, Anja, Platzer, Matthias, Yang, Yun-Gui, Rudolph, Karl Lenhard, Wang, Zhao-Qi
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475398/
https://ncbi.nlm.nih.gov/pubmed/25770585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489947
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