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Smg6/Est1 licenses embryonic stem cell differentiation via nonsense-mediated mRNA decay
Nonsense-mediated mRNA decay (NMD) is a post-transcriptional mechanism that targets aberrant transcripts and regulates the cellular RNA reservoir. Genetic modulation in vertebrates suggests that NMD is critical for cellular and tissue homeostasis, although the underlying mechanism remains elusive. H...
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| Publicat a: | EMBO J |
|---|---|
| Autors principals: | , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BlackWell Publishing Ltd
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4475398/ https://ncbi.nlm.nih.gov/pubmed/25770585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489947 |
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