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REV7/MAD2L2: the multitasking maestro emerges as a barrier to recombination
REV7/MAD2L2 plays important roles in translesion DNA synthesis and mitotic control. Two new papers extend its gamut by revealing its unexpected participation in pathway choice during DNA double-strand break repair. By inhibiting 5′ DNA end resection downstream of 53BP1 and RIF1, REV7/MAD2L2 promotes...
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| Publicado en: | EMBO J |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BlackWell Publishing Ltd
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4475396/ https://ncbi.nlm.nih.gov/pubmed/25896508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201591697 |
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