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REV7/MAD2L2: the multitasking maestro emerges as a barrier to recombination

REV7/MAD2L2 plays important roles in translesion DNA synthesis and mitotic control. Two new papers extend its gamut by revealing its unexpected participation in pathway choice during DNA double-strand break repair. By inhibiting 5′ DNA end resection downstream of 53BP1 and RIF1, REV7/MAD2L2 promotes...

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Bibliografiska uppgifter
I publikationen:EMBO J
Huvudupphovsman: Sale, Julian E
Materialtyp: Artigo
Språk:Inglês
Publicerad: BlackWell Publishing Ltd 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475396/
https://ncbi.nlm.nih.gov/pubmed/25896508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201591697
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