載入...
Genetic ablation of ataxin-2 increases several global translation factors in their transcript abundance but decreases translation rate
Spinocerebellar ataxia type 2 (SCA2) and amyotrophic lateral sclerosis (ALS) are neurodegenerative disorders, caused or modified by an unstable CAG-repeat expansion in the SCA2 gene, which encodes a polyglutamine (polyQ) domain expansion in ataxin-2 (ATXN2). ATXN2 is an RNA-binding protein and inter...
Na minha lista:
| 發表在: | Neurogenetics |
|---|---|
| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Springer Berlin Heidelberg
2015
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4475250/ https://ncbi.nlm.nih.gov/pubmed/25721894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10048-015-0441-5 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|