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N-linked sugar-regulated protein folding and quality control in the ER
Asparagine-linked glycans (N-glycans) are displayed on the majority of proteins synthesized in the endoplasmic reticulum (ER). Removal of the outermost glucose residue recruits the lectin chaperone malectin possibly involved in a first triage of defective polypeptides. Removal of a second glucose pr...
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| Udgivet i: | Semin Cell Dev Biol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4474783/ https://ncbi.nlm.nih.gov/pubmed/25534658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2014.12.001 |
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