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Protein Folding and Quality Control in the ER

The endoplasmic reticulum (ER) uses an elaborate surveillance system called the ER quality control (ERQC) system. The ERQC facilitates folding and modification of secretory and membrane proteins and eliminates terminally misfolded polypeptides through ER-associated degradation (ERAD) or autophagic d...

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Bibliografiske detaljer
Main Authors: Araki, Kazutaka, Nagata, Kazuhiro
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220362/
https://ncbi.nlm.nih.gov/pubmed/21875985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a007526
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