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N-linked sugar-regulated protein folding and quality control in the ER

Asparagine-linked glycans (N-glycans) are displayed on the majority of proteins synthesized in the endoplasmic reticulum (ER). Removal of the outermost glucose residue recruits the lectin chaperone malectin possibly involved in a first triage of defective polypeptides. Removal of a second glucose pr...

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書目詳細資料
發表在:Semin Cell Dev Biol
Main Authors: Tannous, Abla, Pisoni, Giorgia Brambilla, Hebert, Daniel N., Molinari, Maurizio
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474783/
https://ncbi.nlm.nih.gov/pubmed/25534658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2014.12.001
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