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Generation of Multicellular Tumor Spheroids with Microwell-Based Agarose Scaffolds for Drug Testing

Three dimensional multicellular aggregate, also referred to as cell spheroid or microtissue, is an indispensable tool for in vitro evaluating antitumor activity and drug efficacy. Compared with classical cellular monolayer, multicellular tumor spheroid (MCTS) offers a more rational platform to predi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gong, Xue, Lin, Chao, Cheng, Jian, Su, Jiansheng, Zhao, Hang, Liu, Tianlin, Wen, Xuejun, Zhao, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474551/
https://ncbi.nlm.nih.gov/pubmed/26090664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130348
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