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SpheroidChip: Patterned Agarose Microwell Compartments Harboring HepG2 Spheroids are Compatible with Genotoxicity Testing

Three-dimensional tissue culture models are emerging as effective alternatives to animal testing. They are especially beneficial for liver toxicity studies, enabling hepatocytes to display improved levels of liver-specific functions. One common model is hepatocyte spheroids, which are spontaneously...

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Bibliografiske detaljer
Udgivet i:ACS Biomater Sci Eng
Main Authors: Chao, Christy, Ngo Le, P., Engelward, Bevin P.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7603797/
https://ncbi.nlm.nih.gov/pubmed/33145399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsbiomaterials.9b01951
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