Generation of Multicellular Tumor Spheroids with Microwell-Based Agarose Scaffolds for Drug Testing

Three dimensional multicellular aggregate, also referred to as cell spheroid or microtissue, is an indispensable tool for in vitro evaluating antitumor activity and drug efficacy. Compared with classical cellular monolayer, multicellular tumor spheroid (MCTS) offers a more rational platform to predi...

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Udgivet i:PLoS One
Main Authors: Gong, Xue, Lin, Chao, Cheng, Jian, Su, Jiansheng, Zhao, Hang, Liu, Tianlin, Wen, Xuejun, Zhao, Peng
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474551/
https://ncbi.nlm.nih.gov/pubmed/26090664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130348
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