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Oncogenes and tumor suppressor genes: comparative genomics and network perspectives

BACKGROUND: Defective tumor suppressor genes (TSGs) and hyperactive oncogenes (OCGs) heavily contribute to cell proliferation and apoptosis during cancer development through genetic variations such as somatic mutations and deletions. Moreover, they usually do not perform their cellular functions ind...

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Podrobná bibliografie
Vydáno v:BMC Genomics
Hlavní autoři: Zhu, Kevin, Liu, Qi, Zhou, Yubo, Tao, Cui, Zhao, Zhongming, Sun, Jingchun, Xu, Hua
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474543/
https://ncbi.nlm.nih.gov/pubmed/26099335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-16-S7-S8
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