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Oncogenes and tumor suppressor genes: comparative genomics and network perspectives

BACKGROUND: Defective tumor suppressor genes (TSGs) and hyperactive oncogenes (OCGs) heavily contribute to cell proliferation and apoptosis during cancer development through genetic variations such as somatic mutations and deletions. Moreover, they usually do not perform their cellular functions ind...

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Dettagli Bibliografici
Pubblicato in:BMC Genomics
Autori principali: Zhu, Kevin, Liu, Qi, Zhou, Yubo, Tao, Cui, Zhao, Zhongming, Sun, Jingchun, Xu, Hua
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474543/
https://ncbi.nlm.nih.gov/pubmed/26099335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-16-S7-S8
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