Genomic imbalances pinpoint potential oncogenes and tumor suppressors in Wilms tumors

BACKGROUND: Wilms tumor (WT) has a not completely elucidated pathogenesis. DNA copy number alterations (CNAs) are common in cancer, and often define key pathogenic events. The aim of this work was to investigate CNAs in order to disclose new candidate genes for Wilms tumorigenesis. RESULTS: Array-CG...

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Publicado en:Mol Cytogenet
Autores principales: Krepischi, A. C. V., Maschietto, M., Ferreira, E. N., Silva, A. G., Costa, S. S., da Cunha, I. W., Barros, B. D. F., Grundy, P. E., Rosenberg, C., Carraro, D. M.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765068/
https://ncbi.nlm.nih.gov/pubmed/26913079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-016-0227-y
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