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A computational method for clinically relevant cancer stratification and driver mutation module discovery using personal genomics profiles

BACKGROUND: Personalized genomics instability, e.g., somatic mutations, is believed to contribute to the heterogeneous drug responses in patient cohorts. However, it is difficult to discover personalized driver mutations that are predictive of drug sensitivity owing to diverse and complex mutations...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Wang, Lin, Li, Fuhai, Sheng, Jianting, Wong, Stephen TC
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474541/
https://ncbi.nlm.nih.gov/pubmed/26099165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-16-S7-S6
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