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DrugComboRanker: drug combination discovery based on target network analysis

Motivation: Currently there are no curative anticancer drugs, and drug resistance is often acquired after drug treatment. One of the reasons is that cancers are complex diseases, regulated by multiple signaling pathways and cross talks among the pathways. It is expected that drug combinations can re...

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Podrobná bibliografie
Hlavní autoři: Huang, Lei, Li, Fuhai, Sheng, Jianting, Xia, Xiaofeng, Ma, Jinwen, Zhan, Ming, Wong, Stephen T.C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058933/
https://ncbi.nlm.nih.gov/pubmed/24931988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu278
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