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DrugComboRanker: drug combination discovery based on target network analysis

Motivation: Currently there are no curative anticancer drugs, and drug resistance is often acquired after drug treatment. One of the reasons is that cancers are complex diseases, regulated by multiple signaling pathways and cross talks among the pathways. It is expected that drug combinations can re...

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Detalhes bibliográficos
Main Authors: Huang, Lei, Li, Fuhai, Sheng, Jianting, Xia, Xiaofeng, Ma, Jinwen, Zhan, Ming, Wong, Stephen T.C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058933/
https://ncbi.nlm.nih.gov/pubmed/24931988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu278
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